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Drug-fiber compatibility tests of ethambutol and linezolid in the HFS-TB Expected (dashed line) and observed (solid lines) pharmacokinetic (PK) profiles of (a) ethambutol and (b) linezolid, sampled from the intra-capillary space (ICS; green line) and extra-capillary space (ECS; purple line) of <t>polysulfone</t> (PS), polyvinylidene fluoride (PVDF), and cellulose <t>cartridges.</t> Targeted PK parameters for each antibiotic are described in . Drug concentration values are provided in . EMB, ethambutol, LZD, linezolid.
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polysulfone cartridges  (FiberCell Systems)
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Drug-fiber compatibility tests of ethambutol and linezolid in the HFS-TB Expected (dashed line) and observed (solid lines) pharmacokinetic (PK) profiles of (a) ethambutol and (b) linezolid, sampled from the intra-capillary space (ICS; green line) and extra-capillary space (ECS; purple line) of <t>polysulfone</t> (PS), polyvinylidene fluoride (PVDF), and cellulose <t>cartridges.</t> Targeted PK parameters for each antibiotic are described in . Drug concentration values are provided in . EMB, ethambutol, LZD, linezolid.
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Drug-fiber compatibility tests of ethambutol and linezolid in the HFS-TB Expected (dashed line) and observed (solid lines) pharmacokinetic (PK) profiles of (a) ethambutol and (b) linezolid, sampled from the intra-capillary space (ICS; green line) and extra-capillary space (ECS; purple line) of <t>polysulfone</t> (PS), polyvinylidene fluoride (PVDF), and cellulose <t>cartridges.</t> Targeted PK parameters for each antibiotic are described in . Drug concentration values are provided in . EMB, ethambutol, LZD, linezolid.
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Drug-fiber compatibility tests of ethambutol and linezolid in the HFS-TB Expected (dashed line) and observed (solid lines) pharmacokinetic (PK) profiles of (a) ethambutol and (b) linezolid, sampled from the intra-capillary space (ICS; green line) and extra-capillary space (ECS; purple line) of <t>polysulfone</t> (PS), polyvinylidene fluoride (PVDF), and cellulose <t>cartridges.</t> Targeted PK parameters for each antibiotic are described in . Drug concentration values are provided in . EMB, ethambutol, LZD, linezolid.
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polysulfone membrane dialyzer  (Asahi Kasei Corporation)
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Asahi Kasei Corporation polysulfone membrane dialyzer
Drug-fiber compatibility tests of ethambutol and linezolid in the HFS-TB Expected (dashed line) and observed (solid lines) pharmacokinetic (PK) profiles of (a) ethambutol and (b) linezolid, sampled from the intra-capillary space (ICS; green line) and extra-capillary space (ECS; purple line) of <t>polysulfone</t> (PS), polyvinylidene fluoride (PVDF), and cellulose <t>cartridges.</t> Targeted PK parameters for each antibiotic are described in . Drug concentration values are provided in . EMB, ethambutol, LZD, linezolid.
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Image Search Results


Drug-fiber compatibility tests of ethambutol and linezolid in the HFS-TB Expected (dashed line) and observed (solid lines) pharmacokinetic (PK) profiles of (a) ethambutol and (b) linezolid, sampled from the intra-capillary space (ICS; green line) and extra-capillary space (ECS; purple line) of polysulfone (PS), polyvinylidene fluoride (PVDF), and cellulose cartridges. Targeted PK parameters for each antibiotic are described in . Drug concentration values are provided in . EMB, ethambutol, LZD, linezolid.

Journal: iScience

Article Title: An assay toolkit for anti-tuberculosis drugs in the hollow fiber system

doi: 10.1016/j.isci.2026.115292

Figure Lengend Snippet: Drug-fiber compatibility tests of ethambutol and linezolid in the HFS-TB Expected (dashed line) and observed (solid lines) pharmacokinetic (PK) profiles of (a) ethambutol and (b) linezolid, sampled from the intra-capillary space (ICS; green line) and extra-capillary space (ECS; purple line) of polysulfone (PS), polyvinylidene fluoride (PVDF), and cellulose cartridges. Targeted PK parameters for each antibiotic are described in . Drug concentration values are provided in . EMB, ethambutol, LZD, linezolid.

Article Snippet: Medium-size polysulfone cartridges , FiberCell Systems , Cat# C2011.

Techniques: Concentration Assay

Drug-fiber compatibility tests of isoniazid, clarithromycin, moxifloxacin, rifampicin and rifapentine in the HFS-TB Expected (dashed line) and observed (solid lines) pharmacokinetic (PK) profiles of (a) isoniazid, (b) clarithromycin, (c) moxifloxacin, (d) rifampicin, and (e) rifapentine, sampled from the intra-capillary space (ICS; green line) and extra-capillary space (ECS; purple line) of polysulfone (PS), polyvinylidene fluoride (PVDF), and cellulose cartridges. Targeted PK parameters for each antibiotic are described in . Drug concentration values are provided in . CLA, clarithromycin; INH, isoniazid; MXF, moxifloxacin; RMP, rifampicin; RPT, rifapentine.

Journal: iScience

Article Title: An assay toolkit for anti-tuberculosis drugs in the hollow fiber system

doi: 10.1016/j.isci.2026.115292

Figure Lengend Snippet: Drug-fiber compatibility tests of isoniazid, clarithromycin, moxifloxacin, rifampicin and rifapentine in the HFS-TB Expected (dashed line) and observed (solid lines) pharmacokinetic (PK) profiles of (a) isoniazid, (b) clarithromycin, (c) moxifloxacin, (d) rifampicin, and (e) rifapentine, sampled from the intra-capillary space (ICS; green line) and extra-capillary space (ECS; purple line) of polysulfone (PS), polyvinylidene fluoride (PVDF), and cellulose cartridges. Targeted PK parameters for each antibiotic are described in . Drug concentration values are provided in . CLA, clarithromycin; INH, isoniazid; MXF, moxifloxacin; RMP, rifampicin; RPT, rifapentine.

Article Snippet: Medium-size polysulfone cartridges , FiberCell Systems , Cat# C2011.

Techniques: Concentration Assay

Drug-fiber compatibility tests of pretomanid, delamanid, and bedaquiline in the HFS-TB Expected (dashed line) and observed (solid lines) pharmacokinetic (PK) profiles of (a) pretomanid, (b) delamanid, and (c) bedaquiline, sampled from the intra-capillary space (ICS; green line) and extra-capillary space (ECS; purple line) of polysulfone (PS), polyvinylidene fluoride (PVDF), and cellulose cartridges. Targeted PK parameters for each antibiotic are described in . Drug concentration values are provided in . BDQ, bedaquiline; DLM, delamanid; PTD, pretomanid.

Journal: iScience

Article Title: An assay toolkit for anti-tuberculosis drugs in the hollow fiber system

doi: 10.1016/j.isci.2026.115292

Figure Lengend Snippet: Drug-fiber compatibility tests of pretomanid, delamanid, and bedaquiline in the HFS-TB Expected (dashed line) and observed (solid lines) pharmacokinetic (PK) profiles of (a) pretomanid, (b) delamanid, and (c) bedaquiline, sampled from the intra-capillary space (ICS; green line) and extra-capillary space (ECS; purple line) of polysulfone (PS), polyvinylidene fluoride (PVDF), and cellulose cartridges. Targeted PK parameters for each antibiotic are described in . Drug concentration values are provided in . BDQ, bedaquiline; DLM, delamanid; PTD, pretomanid.

Article Snippet: Medium-size polysulfone cartridges , FiberCell Systems , Cat# C2011.

Techniques: Concentration Assay

Optimization approach to use bedaquiline in the HFS-TB Observed pharmacokinetic (PK) profiles of bedaquiline, sampled from the extra-capillary space (ECS) of polysulfone (PS), polyvinylidene fluoride (PVDF), and cellulose HFS-TB cartridges. The targeted median concentration at protein-unbound steady state in the lung (C med, ss = 0.061 μg/mL) is indicated in and represented in the graphs by a dashed line. Drug concentration values are provided in . BDQ, bedaquiline.

Journal: iScience

Article Title: An assay toolkit for anti-tuberculosis drugs in the hollow fiber system

doi: 10.1016/j.isci.2026.115292

Figure Lengend Snippet: Optimization approach to use bedaquiline in the HFS-TB Observed pharmacokinetic (PK) profiles of bedaquiline, sampled from the extra-capillary space (ECS) of polysulfone (PS), polyvinylidene fluoride (PVDF), and cellulose HFS-TB cartridges. The targeted median concentration at protein-unbound steady state in the lung (C med, ss = 0.061 μg/mL) is indicated in and represented in the graphs by a dashed line. Drug concentration values are provided in . BDQ, bedaquiline.

Article Snippet: Medium-size polysulfone cartridges , FiberCell Systems , Cat# C2011.

Techniques: Concentration Assay